Liver function evaluation using L-[1-13C] phenylalanine breath test
نویسندگان
چکیده
منابع مشابه
Clinical research on liver reserve function by 13C-phenylalanine breath test in aged patients with chronic liver diseases
BACKGROUND The objective of this study was to investigate whether the 13C-phenylalanine breath test could be useful for the evaluation of hepatic function in elderly volunteers and patients with chronic hepatitis B and liver cirrhosis. METHODS L-[1-13C] phenylalanine was administered orally at a dose of 100 mg to 55 elderly patients with liver cirrhosis, 30 patients with chronic hepatitis B a...
متن کامل13C-breath tests for clinical investigation of liver mitochondrial function.
BACKGROUND Mitochondria play a major role in cell energetic metabolism; therefore, mitochondrial dysfunction inevitably participates in or even determines the onset and progression of chronic liver diseases. The assessment of mitochondrial function in vivo, by providing more insight into the pathogenesis of liver diseases, would be a helpful tool to study specific hepatic functions and to devel...
متن کامل13C-breath tests in hepatology (cytosolic liver function).
13C-phenylalanine (PheBT) and 13C-galactose breath tests (GBT) explore non invasively the hepatic functional mass by measuring two enzymatic activities localized into the cytosol of liver cells: the phenylalanine hydroxylase (which converts phenylalanine into tyrosine) and the galactose kinase (which catalyzes the ATP-dependent phosphorylation of galactose to galactose 1-phosphate). Both BTs ar...
متن کامل13C-breath tests in the study of mitochondrial liver function.
Breath tests for "dynamic" liver function evaluation have been proposed several years ago. A variety of carbon-labelled breath tests for the assessment of mitochondrial, microsomal and cytosolic liver function have been described with the aim to increase data on liver disease staging, prognosis, and response to therapy. In the last years a great interest is developed about the use of breath tes...
متن کامل13C-methionine breath tests for mitochondrial liver function assessment.
13C-methionine breath test has been proposed as a non-invasive tool for the assessment of human hepatic mithocondrial function. Two methionine breath labeled with 13C in differents point of his molecular structure have been used for breath test analisys. Aim of this study was to compare two differently 13C-labeled methionines in the evaluation of mitochondrial oxidation in basal conditions and ...
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ژورنال
عنوان ژورنال: Journal of Japan Association on Odor Environment
سال: 2006
ISSN: 1348-2904,1349-7847
DOI: 10.2171/jao.37.105